The following is a partial listing of publications incorporating Mouse Specifics instrumentation. Some of these you can grab, others you might need to ask us for because of copyright laws. Enjoy!
David F. Wozniak, Pamela Valnegri, Joshua T. Dearborn, Stephen C. Fowler, and Azad Bonni. 2019. Conditional knockout of UBC13 produces disturbances in gait and spontaneous locomotion and exploration in mice. Sci Rep. 9: 4379. Read Abstract
Feng H, Larrivee CL, Demireva EY, Xie H, Leipprandt JR, Neubig RR. 2019. Mouse models of GNAO1-associated movement disorder: Allele- and sex-specific differences in phenotypes. PLoS One Jan 25;14(1) Read Abstract
Robertson L, Featherby T, Howell S, Hughes J, Thomas P. 2019. Paroxysmal and cognitive phenotypes in Prrt2 mutant mice. Genes Brain Behav. Jun;18(5):e12566 Read Abstract
Falk DJ, Galatas T, Todd AG, Soto EP, Harris AB, Notterpek L. 2018. Locomotor and skeletal muscle abnormalities in trembler J neuropathic mice. Muscle Nerve. Apr;57(4):664-671. Read Abstract
Claghorn, G. C., Z. Thompson, J. C. Kay, G. Ordonez, T. G. Hampton, and T. Garland, Jr. 2017. Selective breeding and short-term access to a running wheel alter stride characteristics in house mice. Physiological and Biochemical Zoology 90:533–545. Read Abstract
Connell JW, Allison R, Reid E. Quantitative Gait Analysis Using a Motorized Treadmill System Sensitively Detects Motor Abnormalities in Mice Expressing ATPase Defective Spastin. PLoS One. 2016 Mar 28;11(3):e0152413. doi: 10.1371/journal.pone.0152413. eCollection 2016. Read Article
Heuermann RJ, et al. Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy. Neurobiol Dis. 2016 Jan;85:81-92. doi:10.1016/j.nbd.2015.10.005. Read Abstract
Hung YH, Walterfang M, Churilov L et al. Neurological Dysfunction in Early Maturity of a Model for Niemann-Pick C1 Carrier Status. Neurotherapeutics. 2016 Mar 4. [Epub ahead of print] Read Article
Miyuki Sakuma, et al. Lack of motor recovery after prolonged denervation of the neuromuscular junction is not due to regenerative failure. Eur J Neurosci. 2016 Feb;43(3):451-62. doi: 10.1111/ejn.13059. Epub 2015 Sep 28. Read Abstract
Xiao J, et al. Motor phenotypes and molecular networks associated with germline deficiency of Ciz1. Exp Neurol. 2016 Sep;283(Pt A):110-20. doi: 10.1016/j.expneurol.2016.05.006. Epub 2016 May 7. Read Abstract
Chen L, et al. A53T human α-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration. J Neurosci. 2015 Jan 21;35(3):890-905. Read Abstrac
Del Mar N, et al. A novel closed-body model of spinal cord injury caused by high-pressure air blasts produces extensive axonal injury and motor impairments. Exp Neurol. 2015 Sep;271:53-71. Read Abstract
Gennarino VA et al. Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels. Cell. 2015 Mar 12;160(6):1087-98. doi: 10.1016/j.cell.2015.02.012. Read Article
Jara JH, et al. Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function. Cereb Cortex. 2015 Nov 25; (11):4259-72 Read Abstract
Lambert CS, et al . Analysis of gait in rats with olivocerebellar lesions and ability of the nicotinic acetylcholine receptor agonist varenicline to attenuate impairments. Behav Brain Res. 2015 Jun 3. pii: S0166-4328(15)30025-5. doi: 10.1016/j.bbr.2015.05.056. Read Abstract
Lasagna-Reeves CA, et al. Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes. Elife. 2015 Dec 17;4. pii: e10891. doi: 10.7554/eLife.10891. Read Article
Liu YB, Tewari A, Salameh J, et al. A dystonia-like movement disorder with brain and spinal neuronal defects is caused by mutation of the mouse laminin β1 subunit, Lamb1. Elife. 2015 Dec 24;4. pii: e11102. doi: 10.7554/eLife.11102. Read Abstract
Neckel ND. Methods to quantify the velocity dependence of common gait measurements from automated rodent gait analysis devices. J Neurosci Methods. 2015 253:244-53. Read Abstract
Nori S, et al. Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: oncogenic transformation with epithelial-mesenchymal transition. Stem Cell Reports. 2015 Mar 10;4(3):360-73. Read Abstract
Pappas SS, et al. Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons. Elife. 2015 Jun 8;4:e08352 Read Abstract
Poulet B, et al. Intermittent applied mechanical loading induces subchondral bone thickening that may be intensified locally by contiguous articular cartilage lesions. Osteoarthritis Cartilage. 2015 Jun;23(6):940-8. Read Abstract
Rothaug M, et al. LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease. Acta Neuropathol Commun. 2015 Jan 31;3:6. Read Abstract
Samantaray S, et al. Inhibition of calpain activation protects MPTP-induced nigral and spinal cord neurodegeneration, reduces inflammation, and improves gait dynamics in mice. Mol Neurobiol. 2015 52(2):1054-66. Read Abstract
Sashindranath M, et al.. Evaluation of gait impairment in mice subjected to craniotomy and traumatic brain injury. Behav Brain Res. 2015 Jun 1;286:33-8. doi: 10.1016/j.bbr.2015.02.038. Read Abstract
Spinelli KJ, et al. Curcumin Treatment Improves Motor Behavior in α-Synuclein Transgenic Mice. PLoS One. 2015 Jun 2;10(6):e0128510. doi: 10.1371/journal.pone.0128510. eCollection 2015 Read Abstract
Wright DJ, et al. N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington’s disease. Transl Psychiatry 2015 5:e492. doi:10.1038/tp.2014.131. Read Abstract
Yuengert et al. Origin of a non-Clarke’s column division of the dorsal spinocerebellar tract and the role of caudal proprioceptive neurons in motor function. Cell Rep. 2015 Nov 10; 13(6): 1258–1271. Read Abstract
Zhang B, et al. Age decreases macrophage IL-10 expression: Implications for functional recovery and tissue repair in spinal cord injury. Exp Neurol. 2015 273:83-91. Read Abstract
Eftaxiopoulou T, et al. Gait compensations in rats after a temporary nerve palsy quantified using temporo-spatial and kinematic parameters. J Neurosci Methods. 2014; 232:16-23. Read Abstract
Jantzie LL, et al. Complex pattern of interaction between in utero hypoxia-ischemia and intra-amniotic inflammation disrupts brain development and motor function. J Neuroinflammation. 2014 11:131 Read Abstract
Lambert CS, et al. Gait analysis and the cumulative gait index (CGI): Translational tools to assess impairments exhibited by rats with olivocerebellar ataxia. Behav Brain Res. 2014 274:334-43. Read Abstract
Lu W, et al. Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson’s-like movement disorder. Nat Commun. 2014 Sep 15;5:4930 Read Abstract
Piochon C, et al. Cerebellar plasticity and motor learning deficits in a copy-number variation mouse model of autism. Nat Commun. 2014 5:5586. Read Abstract
Cops EJ, et al. Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait. See comment in PubMed Commons below Exp Neurol. 2013 Nov;249:8-19. doi: 10.1016/j.expneurol.2013.08.001. Read Abstract
Dorman CW, et al. A comparison of DigiGait™ and TreadScan™ imaging systems: assessment of pain using gait analysis in murine monoarthritis. See comment in PubMed Commons below J Pain Res. 2013 Dec 24;7:25-35. doi: 10.2147/JPR.S52195. Read Abstract
Hansen ST, Pulst SM. Response to ethanol induced ataxia between C57BL/6J and 129X1/SvJ mouse strains using a treadmill based assay. Pharmacol Biochem Behav. 2013 Jan;103(3):582-8. doi: 10.1016/j.pbb.2012.10.010. Epub 2012 Oct 24 Read Abstract
Paumier KL, et al. Behavioral characterization of A53T mice reveals early and late stage deficits related to Parkinson’s disease. PLoS One. 2013 Aug 1;8(8):e70274. doi: 10.1371/journal.pone.0070274. Print 2013 Read Abstract
Takano M, et al. In vivo tracing of neural tracts in tiptoe walking Yoshimura mice by diffusion
tensor tractography. Spine (Phila Pa 1976). 2013 Jan 15;38(2):E66-72 Read Abstract
Glajch KE, et al. Sensorimotor assessment of the unilateral 6-hydroxydopamine mouse model of Parkinson’s disease. Behavioural Brain Research. 2012 May 1;230(2):309-16. doi: 10.1016/j.bbr.2011.12.007. 2012. Read Abstract
Gonzalez-Reyes LE, et al. Sonic Hedgehog Maintains Cellular and Neurochemical Homeostasis in the Adult Nigrostriatal Circuit. Neuron. 2012 July 26; 75(2): 306–319. doi: 10.1016/j.neuron.2012.05.018. Read Abstract
Hampton TG, et al. Gait Disturbances in Dystrophic Hamsters. Journal of Biomedicine and Biotechnology. Volume 2011 (2011), Article ID 235354, 8 pages doi:10.1155/2011/235354. Read Abstract
Goldberg N, et al. Profiling Changes in Gait Dynamics Resulting From Progressive 1-Methyl-4-Phenyl-1,2,3, 6-Tetrahydropyridine-Induced Nigrostriatal Lesioning. J Neurosci Res. 2011 Oct;89(10):1698-706. doi: 10.1002/jnr.22699.
Gomez C. et al. Skeletal Muscle IP3R1 Receptors Amplify Physiological and Pathological Synaptic Calcium Signals. The Journal of Neuroscience. 2011 26 Oct;31(43): 15269-15283 Read Abstract
Gong P, et al. Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice. Molecular Neurodegeneration. 2011 Dec 28;6:87. doi: 10.1186/1750-1326-6-87. Read Abstract
Kam GL. Determination of disease progression with early toxin-induced neuropathology in the aging mutant SOD mouse model of amyotrophic lateral sclerosis. A thesis submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in The Faculty of Graduate Studies (Experimental Medicine) The University of British Columbia (Vancouver) December 2011 Read Abstract
Mancuso R, et al. Evolution of gait abnormalities in SOD1(G93A) transgenic mice. Brain Res. 2011 Aug 11;1406:65-73. Epub 2011 Jul 5. Read Abstract
Puram SV, et al. A TRPC5-regulated calcium signaling pathway controls dendrite patterning in the mammalian brain. Genes Dev. 2011 December 15; 25(24): 2659–2673. doi: 10.1101/gad.174060.111 PMCID: PMC3248686 Read Abstract
Ek CJ, et al. Spatio-temporal progression of grey and white matter damage following contusion injury in rat spinal cord. PLoS One. 2010 Aug 9;5(8):e12021. Read Abstract
Gómez-Sintes R, Lucas JJ. NFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapy. J Clin Invest. 2010 Jul 1;120(7):2432-45. doi: 10.1172/JCI37873. Epub 2010 Jun 7. Read Abstract
Hampton TG, Amende I. Treadmill Gait Analysis Characterizes Gait Alterations in Parkinson’s Disease and Amyotrophic Lateral Sclerosis Mouse Models. Journal of Motor Behavior. 2010 Jan-Feb;42(1):1-4. doi: 10.1080/00222890903272025. Read Abstract
Kravitz AV, et al. Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia. Nature. 2010 Jul 29;466(7306):622-6. Epub 2010 Jul 7. Read Abstract
Springer JE, et al. The Functional and Neuroprotective Actions of Neu2000, a Dual Acting Pharmacological Agent, in the Treatment of Acute Spinal Cord Injury. J Neurotrauma. 2010 Jan;27(1):139-49
Xu YF, et al. Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice. J Neurosci. 2010 Aug 11; 30(32):10851-9. Read Abstract
Berryman ER, et al. Digigait™ quantitation of gait dynamics in rat rheumatoid arthritis model. J Musculoskelet Neuronal Interact. 2009 9:89-98. Read Abstract
Callaway JK, et al. Assessment of residual function and morphology after spinal cord contusion injury in rats: behavioral and histological evidence. 2009 Australian Neuroscience Annual Meeting.
Crone SA, et al. In Mice Lacking V2a Interneurons, Gait Depends on Speed of Locomotion. The Journal of Neuroscience. 2009 29:7098-7109.
Dai Y, et al. Striatal Expression of a Calmodulin Fragment Improved Motor Function, Weight Loss, and Neuropathology in the R6/2 Mouse Model of Huntington’s Disease. J Neuroscience. 2009 September 16; 29(37):11550 –11559. Read Abstract
Dodge JC, et al. Intracerebroventricular infusion of acid sphingomyelinase corrects CNS manifestations in a mouse model of Niemann–Pick A disease. Experimental Neurology. 2009 215:349-357. Read Abstract
Hurlock EC, et al. Rescue of Motor Coordination by Purkinje Cell-Targeted Restoration of Kv3.3 Channels in Kcnc3-Null Mice Requires Kcnc1. The Journal of Neuroscience. 2009 December 16; 29(50):15735–15744. Read Abstract
Kim HA, et al. Motor impairments in a mouse model of Huntington’s with selective ablation of D-1 Receptor- Expressing neurons in the Striatum. 2009 Australian Neuroscience Annual Meeting.
Lubjuhn J, et al. Functional testing in a mouse stroke model induced by occlusion of the distal middle cerebral artery Journal of Neuroscience Methods. 2009 184:195-103.
Pallier PN, Drew CJG, Morton JA. The detection and measurement of locomotor deficits in a transgenic mouse model of Huntington’s disease are task-and-protocol-dependent: Influence of non-motor factors on locomotor function. Brain Res Bull. 2009 78:347-55.
Piesla MJ, et al. Abnormal gait, due to inflammation but not nerve injury, reflects enhanced nociception in preclinical pain models. Brain Res. 2009 1295:89-98. Read Abstract
Cashman NR, et al. METHODS AND COMPOSITIONS TO TREAT AND DETECT MISFOLDED-SOD1 MEDIATED DISEASES WIPO Patent Application WO/2007/098607. 2008.
Oien DB, et al. MsrA knockout mouse exhibits abnormal behavior and brain dopamine levels. Free Radic Biol Med. 2008 45:193-200. Read Abstract
Rohe, MS. Role of SORLA in the brain and its relevance for Alzheimer disease. Dissertation to obtain the academic degree of Doctor of Natural Sciences (Dr. rer. Nat.) Lodged in the Department of Biology, Chemistry, Pharmacy, Free University of Berlin presented by Mr. Dipl.-Biol. Michael Stephen Rohe August 2008.
Tabata RC, Chu TLH, Shaw CA. Genome British Columbia in Collaboration with the Student Biotechnology Network Research Exchange. Stigmasterol glucoside is a putative Neurotoxin: Behavioral and Neuropathological Evidence. 2008: Program 24.
Cabrera-Salazar MA, et al. Timing of Therapeutic Intervention Determines Functional and Survival Outcomes in a Mouse Model of Late Infantile Batten Disease. Molecular Therapy. 2007 10:1782–1788. Read Abstract
Cummings CJ, et al. Method of treating neurological disorders using clotrimazole and derivatives thereof. United States Patent Application. 2007 0037800. 2008.
Ganguly M, et al. Effects of acute chondroitinase treatment and training on functional recovery following moderate spinal cord injury in rats. Program No. 405.6/TT10. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience. 2007. Online.
Hampton TG, et al. Gait disturbances in BIO 14.6 and BIO TO2 dystrophic hamsters. 2007 Experimental Biology meeting [on CD-ROM]. Abstract #558.3, 2007.
Hampton TG, et al. Does your mouse walk strangely? Gait analysis in rodent models of neuromuscular disease. 2007 BIO International Convention meeting abstracts [Online]. Abstract #4.
Huntington J, et al. Hind limb locomotor recovery following spinal cord injury in the rat: Comparison of automated paw print analysis at different gait speeds, open field scores, and recovery time. Program No. 75.18/GG18. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience. 2007. Online.
Luo E, et al. Neurturin protects against gait impairment and induced unilateral neurodegeneration model. Program No. 265.3/T22. 200. Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience. 2007. Online.
Rane J, et al. Emotional and cognitive deficits observed in early stages of Parkinson’s disease. Program No. 445.1. 2007. Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience. 2007. Online.
Rommelfanger KS, et al. Norepinephrine loss produces more profound motor deficits than MPTP treatment in mice Proc Natl Acad Sci U S A. 2007 104:13804-9. Read Abstract
Theriault BR, et al. Gait analysis of mice emerging from isoflurane anesthesia. 58th AALAS National Meeting. Accepted Abstract, 2007.
Vincelette J, et al. Gait analysis in a murine model of collagen-induced arthritis. Arthritis Res Ther. 2007 9(6):R123. Read Abstract
Zinkhan G. Paw print gait analysis in rats with spinal cord injury. Doctoral Dissertation] Dallas (TX): The University of Texas Southwestern Medical Center at Dallas. 2007.
Hampton TG, et al. Propranolol attenuates sympathetic hyperfunction, delays motor dysfunction, and prolongs life in a mouse model of amyotrophic lateral sclerosis. Eur Heart J. 2006 27(Supp.):2161. 2006. [Online], P5469.
Hampton TG, et al. See how they run: gait in blind mice. Program No. 12.9. 2006 Abstract Viewer/Itinerary Planner. Atlanta, GA: Society for Neuroscience. 2006.
Lee G, et al. Neurotoxic susceptibility in a mouse model of ALS2 as revealed by behavioral analysis. Program No. 671.4. 2006 Abstract Viewer/Itinerary Planner. Atlanta, GA: Society for Neuroscience. 2006.
Piesla MJ, et al. Neuropathic and inflammatory pain alters gait and constitutes a novel measurement of therapeutic efficacy in the rat. Program No. 553.7. 2006 Abstract Viewer/Itinerary Planner. Atlanta, GA: Society for Neuroscience, 2006.
Prior to 2005
Amende I, et al. Gait deterioration in the SOD1 G93A mouse model of ALS Program No. 131.13. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience. 2005. Online.
Hampton TG, et al. Gait deterioration in the SOD1 G93A mouse model of ALS. Program No. 131.13. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience. 2005. Online.
Hampton TG, et al. Gait dynamics in Trisomic mice: Quantitative Neurological Traits of Down Syndrome Physiology & Behavior. 2004 82:381– 389. Read Abstract
Hampton TG, et al. How to characterize gait dynamics in mouse models of neuromuscular disease. Program No. 22.60. 2002 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience. 2002. CD-ROM.
Huebsch KA, et al. Mdm muscular dystrophy: interactions with calpain 3 and a novel functional role for titin’s N2A domain. Hum Mol Genet. 2005 14:2801-11. Read Abstract
Kale A, et al. Early detection of gait abnormalities in the MPTP mouse model of Parkinson’s disease. Movement Disorders. 2005 Congress Abstract Program.
Kale A, et al. Gait dynamics in mouse models of Parkinson’s disease and Huntington’s disease. J Neuroengineering Rehabil. 2005 Jul 25;2:20. Read Abstract
Kale A, et al. Ethanol’s effects on gait dynamics in mice investigated by ventral plane videography Alcohol Clin Exp Res. 2004 28:1839-48. Read Abstract
Li S, et al. Transgenic inhibition of Nogo-66 receptor function allows axonal sprouting and improved locomotion after spinal injury. Mol Cell Neurosci. 2005 1:26-39.
Piskorski K, et al. Non-invasive physiology in conscious mice. 2002 Fourth World Congress Alternatives Congress Trust Proceedings. 2004. ATLA 32, Supplement 1:195–201. Read Abstract
Sharma N, et al. Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation. J Neurosci. 2005 25:5351-5. Read Abstract
Wooley CM, et al. Gait analysis detects early changes in transgenic SOD1(G93A) mice. Muscle Nerve. 2005 32:43-50. Read Abstract